|Game||Tales of Berseria|
|Race|| •Human (former)|
|Japanese Voice Actor||Takako Honda|
Medissa (メディサ Medisa?) is a supporting character in Tales of Berseria. She is a devout woman who condemns the Abbey for killing her daughter who turned into a daemon out of her jealousy of Medissa's fiance.
Despite her resentment toward the Abbey over the death of her daughter, she eventually sides with them in order to prevent cases such as hers from ever happening again. Being receptive to Innominat's power, she becomes a therion sealed within the Faldies Ruins that consumes daemons. In their attempt to retrieve all therions, the group seeks her out and, assuming her to be a victim of the Abbey, attempts to free her upon finding her deep within the ruins. However, she assumes a vicious, Medusa-like form and attacks them.
Defeated, she is forced against her will to go with the group, being taken on the Van Eltia to Titania in order to be kept with the other therions. She is initially bound upon their arrival, but Eleanor Hume opts to release her when she comes into contact with Kamoana, a fellow therion who lost her mother in a similar tragedy. Recognizing her failure and blaming herself for her own daughter's death, Medissa becomes a motherly figure for Kamoana and eventually adopts her as a daughter after her marriage to Dyle at the end of the story, all three resuming their human forms. Medissa represents the "conceit" type of malevolence.